Indian Kashmir officials publish nuke prep warning

SRINAGAR, India Officials in Indian-controlled Kashmir are warning residents to be prepared for a possible nuclear war by building build bomb-proof basements and collecting two weeks' worth of food and water.

Local officials said the advisory was routine, though it was the first time it had been published in a newspaper. They said it did not signal new concerns about a nuclear attack in the region, repeatedly fought over by nuclear-armed rivals India and Pakistan.

A series of deadly skirmishes along the cease-fire line in recent weeks has heightened tensions between the two countries, and the timing of the advisory surprised many residents in Srinagar, the main city in Indian-controlled Kashmir.

"This is fueling an atmosphere of fear. Educating people is fine but not this brazen way," said resident Fayaz Ahmed.

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Pakistan's foreign minister: We will work with India to solve our problems

The notice, published Monday by the Kashmir police in the Greater Kashmir newspaper, advised people to build toilet-equipped basements large enough to house their entire families for two weeks. If there is no basement, residents should construct bunkers in their front yards, the notice advised.

The shelters should be stocked with candles, battery-operated lights and radios, it said, adding that stores of nonperishable food and water should be regularly replaced to ensure it is fresh.

The notice said that during a nuclear attack, motorists should dive out of their cars toward the blast to save themselves from being crushed by their soon-to-be tumbling vehicles.

"Expect some initial disorientation as the blast wave may blow down and carry away many prominent and familiar features," it advises.

It also warns residents to keep people contaminated by fallout out of their shelters.

Yoginder Kaul, inspector-general at the civil defense and state disaster response force, said the advisory was part of a normal campaign to educate the public, and the information has been available on a government website for some time.

"We routinely train and educate people regarding different natural and man-made disasters and that's our duty. This advertisement too was part of such a campaign. Please, let's not read into this beyond that. Let it be clear that this is purely in the nature of educating people and not connected with anything else," he said.

Both India and Pakistan claim the divided Kashmir region in its entirety and have fought two wars over it.

Earlier this month, three Pakistani soldiers and two Indian soldiers were killed in the worst bout of fighting in Kashmir since a cease-fire accord was signed by the countries in 2003.

In light of the violence, Indian Prime Minister Manmohan Singh said Sunday he was reviewing future ties with Pakistan.

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Al Qaeda Commander Killed for the 3rd Time

The second in command of al Qaeda's Yemen affiliate was reportedly killed in an airstrike in Yemen in December, according to a news report by Arabic television network Al Arabiya, the third time the former Guantanamo detainee has been reported dead since 2010.

According to the report, Said al-Shihri died last month after sustaining severe injuries from a joint U.S.-Yemeni airstrike that targeted a convoy in which he was riding. The al Arabiya account, based on information from "family sources," said that the airstrike left al-Shihri in a coma. He allegedly died soon after and was buried in Yemen.

On Tuesday afternoon, hours after the initial report, a Yemeni government official denied having any information regarding the death of al-Shihri, according to Arabic news site al-Bawaba.

No photos of a body have yet surfaced and no mention of his death has appeared on jihadi forums.
This is the third time al-Shihri, the second in command of al Qaeda in the Arabian Peninsula (AQAP), has been reported killed since 2009. In 2010, the Yemeni government claimed it had captured him. In September 2012, Yemeni news sites reported he was killed in an American drone strike.

PHOTOS: Terrorists Who Came Back from the Grave

READ: Gitmo Detainee turned terror commander killed: Reports

Al-Shihri, a "veteran jihadist," traveled to Afghanistan shortly after the Sept. 11, 2001 terror attacks to fight coalition troops, only to be captured weeks later, according to West Point's Combating Terrorism Center. He was sent to the U.S. prison in Guantanamo Bay, Cuba, where he stayed for six years before being released to Saudi Arabia. There, he entered a so-called "jihadi rehab" program that attempted to turn terrorists into art students by getting them to get "negative energy out on paper," as the program's director told ABC News in 2009.

READ: Trading Bombs for Crayons: Terrorists Get 'Art Therapy'

But just months after he supposedly entered the fingerpainting camp, al-Shihri reappeared in Yemen where he was suspected to have been behind a deadly bombing at the U.S. embassy there.

At the time, critics of the "jihadi rehab" program used al-Shihri as evidence that extremists would just go through the motions in order to be freed.

Click Here for the Blotter Homepage.

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Today at New Scientist: 21 January 2013

Twitter reveals how Higgs gossip reached fever pitch

Anyone who fondly remembers the heady days of excitement preceding the Higgs boson announcement last year can now relive the experience

Vibrating navigator shows cyclists the way

A buzzing GPS-fuelled belt that tells cyclists when to turn might help them keep their eyes on the road and save lives

Call off the pregnancy police - women want the truth

Pregnant women can do without being made to feel guilty and burdened by wrong or contradictory advice. Just give them the facts, says Linda Geddes

Supernova-powered bow shock creates cosmic spectacle

The infrared vision of NASA's Spitzer Space Telescope shows how a massive speeding star is electrifying its surroundings

First video of squid sex reveals deep-sea Kama Sutra

Watch a pair of squid caught in the act for the first time in an unexpected sexual position

Let's be clear on health risks from radiation

Should Californians have had iodine after Fukushima? In Radiation Robert Peter Gale and Eric Lax clear up the confusion over radiation and health

Wind power delivers too much to ignore

Although aesthetic concerns need to be heard, qualms about wind's reliability are wide of the mark, argues an energy policy researcher

Quadruple DNA helix discovered in human cells

The classic double helix has been joined by a four-stranded version that may play a role in cancer

Turn up the bass to scare birds away from planes

Subwoofers that blast out sounds too low to be heard by humans can keep birds out of busy air space, and prevent them colliding with planes

Earth may be crashing through dark matter walls

If the universe is a patchwork quilt of exotic force fields, we should be able to detect dark matter whenever we cross between patches

Blinded by sun? Let your steering wheel guide you

A steering wheel that buzzes when drivers are dazzled by bright lights and drift from their lane could help curb accidents

NASA planet-hunter is injured and resting

The Kepler space telescope has put its search for alien Earths on hold while it recovers from a stressed reaction wheel

High-tech Dreamliner's wings clipped by battery trouble

Boeing's 787 Dreamliner is replete with cutting-edge technology. But problems with its complex systems now have the planes grounded around the world

Read More..

Israelis vote in elections seen swinging to the right

JERUSALEM: Israelis vote Tuesday in a general election expected to return Prime Minister Benjamin Netanyahu to power at the head of a government of hardline right-wing and religious parties.

The ballot to choose Israel's 19th parliament is likely to usher in a government that will swing further to the right, undermining the chances of a peace deal with the Palestinians and raising the prospect of greater diplomatic isolation for the Jewish state.

Those elected will face key diplomatic and foreign policy questions, including Iran's nuclear programme, which much of the world believes is a cover for a weapons drive, and pressure to revive peace talks with the Palestinians.

No less pressing are the domestic challenges, including a major budget crisis and looming austerity cuts, which are likely to exacerbate already widespread discontent over spiralling prices.

Opinion polls have consistently shown that Netanyahu's rightwing Likud party, running on a joint list with the hardline secular nationalist Yisrael Beitenu, is well ahead of its rivals.

But as the day of reckoning neared, the numbers showed falling support for Likud-Beitenu, which is now seen taking 32 seats -- 10 fewer than it currently holds -- although the centre-left Labour party, its closest contender, is following a distant second with 17.

Final polls late last week had showed the right-wing-religious bloc taking between 61 and 67 seats, compared with 53 to 57 for the centre-left and Arab parties.

In a largely uneventful campaign, the surprise element has been Naftali Bennett, the young, charismatic new leader of the far-right nationalist religious Jewish Home who took over the party in November and is a rising star for the settler lobby.

The party, which firmly opposes a Palestinian state and won just three seats in 2009, is on course to win 15, making it the second faction in parliament and a likely partner in any future coalition government.

Bennett's explosion onto the political scene has spooked Netanyahu, pundits say, with the premier pushing hard to stem the flow of right-wing votes to Jewish Home by burnishing his own credentials as a defender of Israeli settlement in the occupied territories.

Some 5.65 million Israelis are eligible to vote in Tuesday's parliamentary elections.

Voters will be able to cast ballots at 10,132 polling stations which will open at 0500 GMT and close 15 hours later, with television exit polls due to be broadcast immediately afterwards.

Security has been tightened across the country and more than 20,000 police officers have been deployed to secure the vote.

With Netanyahu almost certain to return to the premier's office, the big question is the makeup of the coalition he will piece together and how it will steer Israel on key issues such as settlement activity, talks with the Palestinians and Iran.

But pundits were unanimous he would pick his natural allies to form the next government, which was widely expected to be dominated by right-wing and religious parties.

"In the next coalition, which will include Likud-Beitenu, Jewish Home, Shas, United Torah Judaism and perhaps Yesh Atid as well, there will be a majority, for the first time in history, for the ultra-Orthodox and religious MPs," wrote Shalom Yerushalmi in Maariv newspaper.

"This is mainly a great victory for the settlers, who have become the leading ideological force in the country."

-AFP/fl

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3 Americans killed in Algeria

STORY HIGHLIGHTS

• NEW: 7 Japanese are confirmed dead, 3 are unaccounted for, a Japanese minister says


• NEW: An Algerian official says the gas plant will reopen and foreign workers will return


• In addition to 37 confirmed dead, 5 hostages are unaccounted for, Algeria's leader says


• The militants, who were of eight nationalities, came from northern Mali

(CNN) -- At least 37 hostages died in the terrorist seizure of a natural gas facility in eastern Algeria and the subsequent special forces assaults on it, the country's prime minister said Monday.

Five other hostages are missing from the In Amenas complex and could be dead, Prime Minister Abdul Malek Sallal said.

Before Sallal's statement, officials from other countries and companies that employed foreign workers at the sprawling plant had confirmed 29 hostage deaths.

Seven of the 37 confirmed dead haven't been identified yet, according to the prime minister. Those who have been identified include seven Japanese, six Filipinos, three Americans, three Britons and one Algerian, officials from those countries said.

Some 29 militants also died, while three were captured, Sallal said, according to the state-run Algerian Press Service.

The standoff ended Saturday, after four days, when Algerian special forces stormed the complex for the second time. The government said it did so because the militants were planning to blow up the installation and flee to neighboring Mali with hostages.

"If it exploded, it could have killed and destroyed anything within 5 kilometers or further," Sallal said.

Read more: Bloody Algeria hostage crisis ends after 'final' assault, officials say

Militant says Mali unrest spurred assault; others say it followed ample planning

The crisis began Wednesday when Islamist extremists in pickup trucks struck the natural gas complex some 50 kilometers (30 miles) west of the Libyan border, gathered the Westerners who worked there into a group and tied them up.

After taking over, the well-armed militants planted explosives throughout the complex, Sallal said. They came from eight countries: Algeria, Tunisia, Egypt, Mali, Niger, Canada and Mauritania.

Algeria's military talked with the militants, but their demands that prisoners in the North African nation be released were deemed unreasonable, according to the prime minister. The country's special forces waged the assaults to free the hostages and were backed by the Algerian Air Force.

Read more: Nations scramble to account for missing after Algeria hostage crisis

At one point, the militants tried to flee the compound in vehicles that carried explosives and three or four hostages as human shields, Sallal said. At least two of the vehicles flipped and exploded during the attempt, he said.

Sallal said the terrorists had entered the country from northern Mali, where Malian and French authorities are battling Islamist rebels.

One-eyed veteran Islamist fighter Moktar Belmoktar has claimed responsibility for the hostage-taking on behalf of his al Qaeda-linked group, according to Mauritania's Sahara Media news agency.

Belmokhtar said the attack was in retaliation for Algeria allowing France to use its airspace to battle Islamist militants in Mali. But regional analysts believe the operation was too sophisticated to have been planned so quickly, and Sallal said the hostage scheme had been hatched over months.

Algerian minister says gas plant will restart, foreign workers will return

The targeted gas facility is run by Algeria's state oil company, in cooperation with foreign firms such as Norway's Statoil and Britain's BP. Some 790 people worked there, including 134 foreign workers, Algeria's prime minister said.

Read more: Algerian forces seek 'peaceful' settlement of dramatic, deadly hostage crisis

British Prime Minister David Cameron said Monday the effort to evacuate workers is complete and that U.K. officials are now focused on bringing the bodies of slain British hostages back home.

Cameron praised Algerian forces for their work in ending the crisis, despite concerns from some nations earlier that the Algerians had unnecessarily put hostages at greater risk.

"This would have been a most-demanding task for security forces anywhere in the world, and we should acknowledge the resolve shown by the Algerians in undertaking it," the British leader said. "The responsibility for these deaths lies squarely with the terrorists."

Such Islamist militant activity is not new to Africa, including recent violence in Mali and Somalia.

Algeria's status as Africa's largest natural gas producer and a major supplier of the product to Europe heightens its importance to those who want to invest there. That interest is coupled with pressure to make sure foreign nationals, and their business ventures, are safe.

Energy and Mining Minister Youcef Yousfi, who a day earlier insisted Algeria can keep its gas facilities secure without foreign forces' help, said he believes the targeted gas facility will be back running "in the shortest possible time" and that foreign workers will soon return. Several foreign companies, including Statoil and BP, evacuated their workers from Algeria after the incident.

"I don't think that these workers have left definitively Algeria," Yousfi told reporters, according to the Algerian Press Service. "Maybe some left ... to reassure their families, but I want to ensure that no company or no worker permanently left the country."

Nations mourn dead, try to account for others

Here is a breakdown on the status of hostages from around the world who were involved in the crisis:

Colombia

Colombia's president said one of its citizens is presumed dead.

France

No known French hostages are unaccounted for, the defense ministry said.

A man identified as Yann Desjeux died after telling French newspaper Sud Ouest that he and 34 other hostages were treated well. It was unclear what led to his death.

Japan

Japanese Vice Foreign Minister Minoru Kiuchi and officials from JGC, a Yokohama-based engineering firm, saw and identified the bodies of seven Japanese citizens killed in the crisis, Chief Cabinet Secretary Yoshihide Suga announced late Monday.

Three Japanese remain unaccounted for, according to Suga.

Malaysia

Three hostages were on their way back home, state media reported. There is a "worrying possibility" that another is dead while a fifth is unaccounted for, the agency said.

Read more: Algeria attack may have link to Libya camps

Norway

Five Norwegians are missing, while eight are safe, according to Norwegian Prime Minister Jens Stoltenberg.

Philippines

Six Filipinos are confirmed dead and four are missing, the nation's foreign affairs ministry said. In addition, 16 Filipinos are alive and accounted for, according to a ministry spokesman.

Romania

One Romanian lost his life while four others were freed, the country's foreign ministry said.

United Kingdom

Three British citizens were killed, the Foreign Office said Sunday. Three other British nationals and a UK resident are also "believed dead," according to British officials. The Foreign Office confirmed the name of one slain hostage, Garry Barlow, in a statement Monday.

"Garry was a loving, devoted family man, he loved life and lived it to the full. He was very much loved by myself, his sons, mother and sister and the rest of his family and friends and will be greatly missed," the Foreign Office quoted his wife, Lorraine, as saying.

Twenty-two other Britons who were taken hostage have safely returned home.

United States

U.S. State Department spokesman Victoria Nuland on Monday said three Americans had been killed and identified them as Victor Lynn Lovelady, Gordon Lee Rowan, and Frederick Buttaccio, who had been previously identified.

Seven U.S. citizens survived the crisis, added Nuland, who declined to comment further citing privacy considerations.

Read more: Algeria attack may have link to Libya camps

CNN's Yoko Wakatsuki and Greg Botelho contributed to this report.

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Obama looks to past to set course for future

News Analysis

President Obama is a student of history - it was no coincidence that he formally announced his run to become the first African-American president back in 2007 at the Old State Capitol in Springfield, Illinois, where Abraham Lincoln delivered his "house divided" speech in 1858 - and his inaugural address today drew an unmistakable line between the nation's past and its prospects for the future.

Play Video

President Obama's second inaugural speech

The president opened his remarks by referencing Lincoln's words from that speech, stating that America came to realize at that point in history that "no union founded on the principles of liberty and equality could survive half-slave and half-free." He grounded his remarks in the Declaration of Independence's claim that "all men are created equal," tying it to both the American Revolution and rules mandating that there is fair play in the free market, to the need for a great nation to "protect its people from life's worst hazards and misfortune."

Later, he again invoked the declaration - though this time, he referred to the notion that "all of us are created equal" - before referencing three landmark moments in the battle for civil rights: The Seneca Falls Convention for women's rights, the clashes in Selma for African-American rights and the riots at New York's Stonewall Inn for gay rights. (The speech marked the first presidential inaugural in which LGBT rights have been referenced.)

He then pivoted from the triumphs of the past to the necessity of continuing the fight, calling for equal pay for women, equal rights for gay men and women, an elimination of long lines to vote, better treatment of immigrants, and, in an indirect reference to his desire to pass gun control legislation, the necessity of children from Detroit to Appalachia to Newtown to know "that they are cared for, and cherished, and always safe from harm."

Play Video

Brinkley on inaugural address: "A great civil rights speech"

At five separate moments in his second inaugural address, delivered to an estimated 500,000 to 700,000 people at the Capitol, Mr. Obama uttered the words "We, the people" - the opening words to the preamble of the Constitution. Those words were deployed to underscore the president's argument that Americans need to recognize that we are all in it together - and that while America celebrates initiative and enterprise, "preserving our individual freedoms ultimately requires collective action."

"For the American people can no more meet the demands of today's world by acting alone than American soldiers could have met the forces of fascism or communism with muskets and militias," he said. "No single person can train all the math and science teachers we'll need to equip our children for the future, or build the roads and networks and research labs that will bring new jobs and businesses to our shores. Now, more than ever, we must do these things together, as one nation, and one people." He went on to add that "we are made for this moment, and we will seize it - so long as we seize it together."

That idea underscored the positions Mr. Obama reiterated during the speech, which at times came closer to a policy-oriented State of the Union Address than an inaugural, which historically tends to be more about soaring rhetoric. (The president will offer his State of the Union on February 12.) In addition to arguing that economic inequality hampers the nation's success, he said that the future depends on harnessing "new ideas and technology to remake our government, revamp our tax code, reform our schools, and empower our citizens with the skills they need to work harder, learn more, and reach higher."

"We do not believe that in this country, freedom is reserved for the lucky, or happiness for the few," said the president. "We recognize that no matter how responsibly we live our lives, any one of us, at any time, may face a job loss, or a sudden illness, or a home swept away in a terrible storm. The commitments we make to each other - through Medicare, and Medicaid, and Social Security - these things do not sap our initiative; they strengthen us. They do not make us a nation of takers; they free us to take the risks that make this country great."

Mr. Obama also fit a call for a renewed focus on fighting climate change - an issue largely absent from his first-term agenda - into the notion of collective action for the common good, saying that "the failure to [address it] would betray our children and future generations."

Play Video

Axelrod on Obama's vision for economy

In addition to climate change, Mr. Obama's second term agenda involves pushing passage of gun control and immigration legislation, overseeing the further implementation of the health care law, winding down the war in Afghanistan, and continuing to try to find some way to come to a major agreement with Republicans to address the nation's massive debt and deficit.

He has signaled that to accomplish these goals, he will take a more confrontational approach with Republicans than he did in his first term -- an approach illustrated by his recent refusal to negotiate on raising the debt limit. His inaugural address offered little in the way of appeals for Washington bipartisanship; instead, Mr. Obama called on Americans in and out of the nation's capitol to come together to help the nation stay on the right path, even if the results are sometimes "imperfect."

"Progress does not compel us to settle centuries-long debates about the role of government for all time - but it does require us to act in our time," he said. "For now decisions are upon us, and we cannot afford delay."

It was an appeal grounded in the notion that America's strength comes from all its citizens, no matter their status. And it was offered by a president who knows the debt he owes to history - a president who sees himself both as a symbol of American progress and a vessel to keep it moving forward.

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Inauguration: 7.5 Things You Should Have Seen

A presidential inauguration is a big, long event that lasts all day and into the night–and who has time to really watch it? People have jobs, ones that don’t let you off for a federal holiday.

Everyone (or, at least, some) will be talking about it, which means potential embarrassment for anyone who doesn’t know what happened. Thankfully, ABC employs  news professionals stationed in Washington, D.C., to pay attention to these kinds of things and boil off some of the less noteworthy or interesting stuff, presenting you with short videos of everything that really mattered. Or at least the things a lot of people were talking about.

A full day of paying attention to President Obama’s second Inauguration leads one of those professionals to offer these 7 1/2 things:

1. Beyonce Sang the National Anthem

Boy, howdy! Did she ever? Beyonce has essentially become the Obama’s go-to female performer: She recorded a music video for Michelle Obama’s “Let’s Move” initiative in 2011, and she performed at the president’s last inauguration in 2009. Her velvety, soulful “Star Spangled Banner” is getting good reviews.

2. Kelly Clarkson Also Sang

Kelly Clarkson is not as “in” with the First Couple as Beyonce seems to be, but they let her sing “My Country ‘Tis of Thee,” and she did a pretty good job with it. This was kind of weird, though, because at one point she said she loved Ron Paul, although she later said she would vote for Obama.

3.  Obama Talked About Gay Rights

This may not seem shocking since more than half the country, including President Obama, supports gay marriage. But the president made a point of mentioning gay rights during his speech, equating the struggles of the LGBT community with those of  past civil rights movements, and in doing so made history.

He name-checked Stonewall, the New York City bar that was raided by police in 1969 sparking riots to protest the anti-gay crackdown. And he actually used the word “gay”: “Our journey is not complete until our gay brothers and sisters are treated like anyone else under the law – for if we are truly created equal, then surely the love we commit to one another must be equal as well,” Obama said in his address.

Plenty of inaugural addresses have been chock full of rhetoric about freedom and equality, but in the last four years, the political culture surrounding gay rights has changed significantly, as more states legalized same-sex marriage and as broad swaths of the country got more comfortable with homosexuality in general. Obama’s “evolution” on gay marriage, and now his inaugural address, have helped signify that change.

4. Joe Biden Made Jokes and Shook Hands With People

Could we expect anything less?

Here’s how the Vice President toasting Sen. Chuck Schumer instead of President Obama at the big luncheon:  ”I raise my glass to a man who never, never, never operates out of fear, only operates out of confidence, and a guy–I’m toasting you, Chuck.” Watch it:

And here he is, scurrying around and jovially shaking hands with people along the parade route:

5. Richard Blanco Read a Poem That Was Sort of Whitman-esque, But Not Entirely

Cuban-born Richard Blanco became America’s first openly gay, Latino Inauguration poet. He read a nine-stanza poem entitled “One Today,” which set a kind of unifying American tableau scene.

6. Obama and Michelle Walked Around Outside The Limo

President Obama walked part of the parade route, from the Capitol to the White House, with Michelle. They waved to people. It is not entirely abnormal for a president to do this at an inaugural parade. But they walked quite a ways.

7. John Boehner: ‘Godspeed’

The speaker of the House presented American flags to Obama and Biden, telling them: “To you gentlemen, I say congratulations and Godspeed.”

7 1/2. Sasha and Malia Were There. 

Obama’s daughters, Sasha and Malia, were there. They didn’t really do much, but they did wear coats of different shades of purple that got a lot of  attention on Twitter.

Reports of the daughters looking at smartphones and applying lip gloss highlighted their day. As did this .gif of Sasha yawning.

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Quadruple DNA helix discovered in human cells

Sixty years after James Watson and Francis Crick established that DNA forms a double helix, a quadruple-stranded DNA helix has turned up.

Quadruple helices that intertwine four, rather than two, DNA strands had been made in the laboratory, but were regarded as curiosities as there was no evidence that they existed in nature. Now, they have been identified in a range of human cancer cells.

The four-stranded packages of DNA, dubbed G-quadruplexes, are formed by the interaction of four guanine bases that together form a square. They appear to be transitory structures, and were most abundant when cells were poised to divide. They appeared in the core of chromosomes and also in telomeres, the caps on the tips of chromosomes that protect them from damage.

Because cancer cells divide so rapidly, and often have defects in their telomeres, the quadruple helix might be a feature unique to cancer cells. If so, any treatments that target them will not harm healthy cells.

"I hope our discovery challenges the dogma that we really understand DNA structure because Watson and Crick solved it in 1953," says Shankar Balasubramanian of the University of Cambridge, UK.

Tagged with antibodies

Balasubramanian's team identified the four-stranded structures in cancer cells with the help of an antibody that attaches exclusively to G-quadruplexes. To stop them from unravelling into the ordinary DNA, they exposed the cells to pyridostatin, a molecule that traps quadruple helices wherever they form.

This enabled the researchers to count how many formed at each stage of cell multiplication. The G-quadruplexes were most abundant in the "S-phase" – when cells replicate their DNA just prior to dividing.

"I expect they will also exist in normal cells, but I predict that there will be differences with cancer cells," says Balasubramanian. His hunch is that the G-quadruplexes are triggered into action by chaotic genomic mutations and reorganisations typical of cancerous or precancerous cells.

"This research further highlights the potential for exploiting these unusual DNA structures to beat cancer, and the next part of this is to figure out how to target them in tumour cells," says Julie Sharp of Cancer Research UK, which funded the research.

Another important question that Balasubramanian's and other teams will try to answer is whether G-quadruplexes play a role in embryo development, and whether such a role is mistakenly reactivated in cancer cells. "We plan to find out whether the quaduplexes are a natural nuisance, or there by design," he says.

Journal reference: Nature Chemistry, DOI: 10.1038/NCHEM.1548

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President Tan confident US will steer world out of uncertainty

SINGAPORE: President Tony Tan Keng Yam has said he is confident that the United States will be able to rise to the occasion of steering of the world out of economic uncertainty, under the leadership of President Barack Obama.

In a congratulatory letter to President Obama on his inauguration for a second term in office, President Tan noted that during his first term, the US averted a financial and economic catastrophe while the lives of many Americans improved.

President Tan said the global economic outlook remains subdued and many countries will continue to look to the US for leadership.

He said he is confident that under President Obama's leadership, as well as the resourcefulness and tenacity of the American spirit, the US will be able to rise to the occasion.

Turning to relations between Singapore and the US, President Tan said both sides enjoy excellent and multifaceted relations underpinned by the US-Singapore Free Trade Agreement and the Strategic Framework Agreement.

Over the last four years, cooperation between both countries has broadened to include education and technical assistance to developing countries, particularly within the Association of Southeast Asian Nations.

President Tan said he looks forward to further enhancing the bilateral relationship.

He also wished President Obama every success during his second term in office.

- CNA/al

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Obama renews his promise to America

Best of 2013 inauguration

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Photos: Best of 2013 inauguration

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Photos: Best of 2013 inauguration

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STORY HIGHLIGHTS

• Quiet official ceremonies for Obama, Biden precede Capitol swearing-in on Monday


• Chief Justice and Obama perform oath flawlessly this time


• Public events will attract large crowds, but smaller than Obama's first inaugural


• Obama has vowed to press for overhaul of immigration policies, find new ways to boost economy

Watch CNN's comprehensive coverage of President Barack Obama's second inauguration this weekend on CNN TV and follow online at CNN.com or via CNN's apps for iPhone, iPad and Android. Then, on Monday, follow our real-time Inauguration Day live blog at cnn.com/conversation. Need other reasons to watch inauguration coverage on CNN's platforms? Click here for our list.

Washington (CNN) -- With the official business of the 57th inauguration out of the way, Washington began preparing Sunday for a day of revelry -- and for the challenges facing President Barack Obama over the next four years.

Satisfying the constitutional obligation to be sworn in on January 20, Obama and Vice President Joe Biden took quiet oaths the day before the public ceremony at the Capitol, which is expected to attract a crowd of up to 800,000 on the National Mall.

Obama will become only the 17th U.S. president to deliver a second inaugural address before leading the traditional parade up Pennsylvania Avenue to the White House.

Presidential inaugurations and oaths

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Monday's events will be smaller than Obama's first inauguration in 2009, when nearly two million people witnessed the swearing-in of the country's first African-American president.

Less intensity this time reflects the reality of second-term presidencies, when the novelty and expectations of a new leader have been replaced with the familiarity and experiences of the first four years.

For Obama, that difference is even sharper.

His historic ascent to the White House in 2008 came with soaring public hopes and expectations for a new kind of governance that would close the vast partisan gulf developed in recent decades.

Obama to acknowledge divided Washington in inaugural address

However, a list of challenges that included an inherited economic recession and repeated battles with congressional Republicans over budgets and spending only hardened the opposing positions in Washington.

Obama's signature achievements, including major reforms of the health care industry and Wall Street, became symbols of political division, with opponents constantly accusing him of hindering needed economic recovery.

A second-term Obama has vowed to press for an overhaul of the nation's immigration policies and new ways to boost the sputtering economy -- proposals that are bound to spark battles with his Republican rivals -- and oversee the implementation of Obamacare.

And the shootings at a Connecticut elementary school last month put the divisive issue of gun control on his immediate agenda.

CNN polling released Sunday showed a majority of Americans -- 54% -- believe Obama will be an outstanding or above average president in his second term, while 43% said he'd be poor or below average.

And while overall, seven in 10 Americans hope the president's policies succeed, only four in 10 Republicans feel that way, with 52% hoping that Obama will fail.

Obama's senior adviser, David Plouffe, said on Sunday that "the challenges and opportunities are enormous" in the president's second term, and that those challenges would be confronted as soon as the inaugural celebrations play out.

The tone of Obama's inaugural address on Monday will be "hopeful," Plouffe told CNN on Sunday, explaining that Obama would "remind the country that our founding principles and values still can guide us in a changing and modern world."

13 reasons to follow the inauguration on CNN platforms

"He's going to talk about the fact that our political system doesn't require us to resolve all of our disputes or settle all of our differences but it doesn't compel us to act where there shouldn't and is common ground," Plouffe added. "He's going to make that point very clearly."

Plouffe underscored that Obama's State of the Union address, to take place February 12, will present a more specific "blueprint" of the next four years.

Obama's swearing-in on Sunday took place in the ornate Blue Room, an oval-shaped reception space in the president's official residence, where he was joined by his wife, Michelle, and his two daughters.

Obama placed his left hand on a Bible held by Mrs. Obama that was from her family. He then raised his right hand.

Chief Justice John Roberts administered the oath - his third time to hold that honor. After Roberts flubbed the order of words during the public ceremony in 2009, a do-over took place in the White House Map Room the next day to erase any question that Obama was officially the president.

Obamas, Bidens participate in National Day of Service

Roberts didn't have any trouble with the oath this time around. He read from a white note card. Slash marks where Roberts paused to have Obama repeat the words were clearly visible.

The event took less than a minute and Obama didn't make any formal remarks or statements.

He did take a moment to hug his wife and daughters, exclaiming: "I did it!"

Justice Sonia Sotomayor performed the honors for Biden at his home at the Naval Observatory in Washington, where the vice president's extended family and a few Cabinet officials gathered to watch the ceremony.

Katy Perry brings 'Fireworks' to inauguration kids' concert

Both Obama and Biden went to Arlington National Cemetery after Biden's swearing-in for a traditional wreath laying.

The president and his family also attended services celebrating the Rev. Martin Luther King Jr. at Metropolitan African Methodist Episcopal Church, one of the most historic churches in Washington.

Inauguration activities kicked off on Saturday with Obama and Mrs. Obama and Biden and his wife, Jill, leading volunteers across the country in National Day of Service Activities.

Later Saturday, singer Katy Perry headlined a concert for children of military families and Washington schoolchildren, hosted by Michelle Obama and Jill Biden. Singer Usher and the cast of the TV show "Glee" were among others who performed.

Sunday evening, the Obamas will watch Latino acts at "In Performance at the Kennedy Center," which is followed by the Let Freedom Ring concert. The Red, White and Blue Inaugural Ball and Hip-Hop Inaugural Ball are also scheduled in the capital.

Viewer's guide to the inauguration

CNN's Tom Cohen, Dana Davidsen, Brianna Keilar, Kevin Liptak, Dan Lothian and Gregory Wallace contributed to this report

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